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  3. Laparoscopic management of bowel endometriosis: resection margins as a predictor of recurrence.
 

Laparoscopic management of bowel endometriosis: resection margins as a predictor of recurrence.

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BORIS DOI
10.7892/boris.67700
Publisher DOI
10.1111/aogs.12490
PubMed ID
25175300
Description
OBJECTIVE

To evaluate possible predictive factors for recurrence after laparoscopic segmental bowel resection for bowel endometriosis.

DESIGN

Cohort study.

SETTING

Academic tertiary referral center.

METHODS

95 symptomatic women with bowel endometriosis who underwent laparoscopic segmental bowel resection at the Endometriosis clinic, University of Berne, between 2002 and 2012 were enrolled. Since 14 women were lost to follow-up, 81 formed the final cohort. Clinical and histological characteristics were examined as possible predictive factors for disease recurrence.

MAIN OUTCOME MEASURES

Recurrence, defined as a subsequent operation due to recurrent endometriosis-associated pain with a histologically confirmed endometriotic lesion.

RESULTS

Recurrence was observed in 13 (16%) patients. Variables that were significantly associated to recurrence by the Cox regression analysis were positive bowel resection margins (hazard ratio 6.5, 95% confidence interval 1.8-23.5, p = 0.005), age <31 years (hazard ratio 5.6, 95% confidence interval 1.7-18.6, p = 0.005) and body mass index ≥23 kg/m(2) (hazard ratio 11.0, 95% confidence interval 2.7-44.6, p = 0.001).

CONCLUSIONS

Positive bowel resection margins as well as age <31 years and body mass index ≥23 kg/m(2) appear to be independent predictors of disease recurrence.
Date of Publication
2014-12
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Keyword(s)
Bowel endometriosis
•
recurrence
•
resection margins
•
segmental resection
Language(s)
en
Contributor(s)
Nirgianakis, Konstantinos
Departement Klinische Forschung, Forschungsgruppe Endometriose und gynäkologische Onkologie
Mc Kinnon, Brettorcid-logo
Departement Klinische Forschung, Forschungsgruppe Endometriose und gynäkologische Onkologie
Imboden, Sara
Departement Klinische Forschung, Forschungsgruppe Endometriose und gynäkologische Onkologie
Knabben, Laura Michelle Tatjana
Departement Klinische Forschung, Forschungsgruppe Endometriose und gynäkologische Onkologie
Gloor, Beat
Universitätsklinik für Viszerale Chirurgie und Medizin, Viszeral- und Transplantationschirurgie
Mueller, Michael
Departement Klinische Forschung, Forschungsgruppe Endometriose und gynäkologische Onkologie
Additional Credits
Departement Klinische Forschung, Forschungsgruppe Endometriose und gynäkologische Onkologie
Universitätsklinik für Viszerale Chirurgie und Medizin, Viszeral- und Transplantationschirurgie
Series
Acta obstetricia et gynecologica Scandinavica
Publisher
Wiley-Blackwell
ISSN
0001-6349
Access(Rights)
restricted
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