Reporting and handling of incomplete outcome data in implant dentistry: A survey of randomized clinical trials.
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BORIS DOI
Publisher DOI
PubMed ID
31746483
Description
AIM
To assess the reporting and handling of incomplete outcome data in randomized clinical trials (RCTs) published in implant dentistry.
MATERIALS AND METHODS
We included RCTs on interventions related to the treatment with dental implants and presented any form of missing data. PubMed, SCOPUS and Cochrane databases were searched for studies published between May 2015 and May 2018. Reporting and handling of missing data at the study level was evaluated using a series of relevant questions. Descriptive data was reported, and univariable analyses were performed to evaluate the association of study variables with quality of reporting and data handling.
RESULTS
One-hundred and thirty-seven RCT reports were included from the 7,116 initially retrieved publications. The reporting of incomplete outcome data varied greatly among the trials and for the different questions. The range of adequately reported questions was between 3.64% (question: comparison of baseline characteristics of all randomised participants) and 100% (question: explicit reporting of missing data). The complete case analysis was the most used (45.3%) approach for incomplete outcome data handling.
CONCLUSIONS
Randomized studies in implant dentistry have room for improvement in both the reporting and the handling of incomplete outcome data.
To assess the reporting and handling of incomplete outcome data in randomized clinical trials (RCTs) published in implant dentistry.
MATERIALS AND METHODS
We included RCTs on interventions related to the treatment with dental implants and presented any form of missing data. PubMed, SCOPUS and Cochrane databases were searched for studies published between May 2015 and May 2018. Reporting and handling of missing data at the study level was evaluated using a series of relevant questions. Descriptive data was reported, and univariable analyses were performed to evaluate the association of study variables with quality of reporting and data handling.
RESULTS
One-hundred and thirty-seven RCT reports were included from the 7,116 initially retrieved publications. The reporting of incomplete outcome data varied greatly among the trials and for the different questions. The range of adequately reported questions was between 3.64% (question: comparison of baseline characteristics of all randomised participants) and 100% (question: explicit reporting of missing data). The complete case analysis was the most used (45.3%) approach for incomplete outcome data handling.
CONCLUSIONS
Randomized studies in implant dentistry have room for improvement in both the reporting and the handling of incomplete outcome data.
Date of Publication
2020-02
Publication Type
Article
Subject(s)
Keyword(s)
Bias methodological study methods randomized controlled trial systematic reviews
Language(s)
en
Contributor(s)
Lieber, Ricarda | |
Faggion, Clovis Mariano |
Additional Credits
Series
Journal of clinical periodontology
Publisher
Wiley
ISSN
0303-6979
Access(Rights)
open.access