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  3. Personality dysfunction according to the DSM-5 Alternative Model of Personality Disorders (AMPD) predicts suicide attempts in clinical high-risk adolescents.
 

Personality dysfunction according to the DSM-5 Alternative Model of Personality Disorders (AMPD) predicts suicide attempts in clinical high-risk adolescents.

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BORIS DOI
10.48620/97154
Publisher DOI
10.1016/j.jad.2026.121811
PubMed ID
41997375
Description
Background
Both personality traits and personality disorders have been linked to suicide risk in youth. The DSM-5 Alternative Model of Personality Disorders (AMPD) allows dimensional assessment of personality pathology, which may enhance prediction of suicide attempts. A recent study found that personality dysfunction (Criterion A of the AMPD) is associated with past suicide attempts in adolescents. Building on this, the present study aimed to investigate the longitudinal relationship between AMPD personality pathology and suicide attempts in adolescents.Methods
Data were drawn from a consecutive clinical cohort study including adolescent patients aged 12 to 18 years (N = 252, 85% female) engaging in risk-taking and self-harming behaviors. Personality dysfunction, maladaptive personality traits, suicide attempts, and depression severity were assessed using standardized interviews and questionnaires at baseline and at two annual follow-ups. 66% of participants completed any follow-up. A Bayesian Structural Equation Modeling framework was used for data analysis.Results
Personality dysfunction predicted suicide attempts over the two-year follow-up (β = 0.38, 95% CI [0.01; 0.73], p = .046). Adding maladaptive personality traits did not add predictive value, while depression severity emerged as a slightly stronger predictor. The effect of personality dysfunction remained stable after accounting for these variables.Conclusions
These findings highlight the value of assessing personality dysfunction in adolescent suicide risk evaluation. Within the AMPD framework, personality dysfunction may be more important than maladaptive traits in predicting suicide attempts. However, analyzing distinct personality functioning domains or maladaptive traits may provide further insight into suicide attempt prediction.
Date of Publication
2026-08-15
Publication Type
Article
Keyword(s)
Adolescence
•
Bayesian Structural Equation Modeling
•
Dimensional personality model
•
Personality disorder
•
Suicidal behavior
Language(s)
en
Contributor(s)
Hess, Lea Kassandra
University Hospital of Child and Adolescent Psychiatry and Psychotherapy
Graduate School for Health Sciences (GHS)
Hertel, Christian
KJP Research Division
Sele, Silvano
KJP Research Division
Reichl, Corinna
University Hospital of Child and Adolescent Psychiatry and Psychotherapy
Cavelti, Marialuisa
University Hospital of Child and Adolescent Psychiatry and Psychotherapy
Koenig, Julian
Kaess, Michael
University Hospital of Child and Adolescent Psychiatry and Psychotherapy
Additional Credits
University Hospital of Child and Adolescent Psychiatry and Psychotherapy
KJP Research Division
Graduate School for Health Sciences (GHS)
Series
Journal of Affective Disorders
Publisher
Elsevier
ISSN
1573-2517
0165-0327
Access(Rights)
open.access
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