Hypereosinophilia driven by GM-CSF in large-cell carcinoma of the lung

Publisher DOI
PubMed ID
22420949
Description
In contrast to leukocytosis, paraneoplastic hypereosinophilia is uncommon in lung cancer. We present a patient with large-cell carcinoma of the lung, in which cancer cells generate large amounts of GM-CSF leading to a leukemoid reaction with prominent hypereosinophilia and potentially involved in autocrine tumor stimulation.
Date of Publication
2012
Publication Type
Article
Subject(s)
Language(s)
en
Contributor(s)
Lammel, Verena
Padberg, Barbara
Zweifel, Roland
Kienle, Dirk L
Reinhart, Walter H
Additional Credits
Series
Lung cancer
Publisher
Elsevier
ISSN
0169-5002
Access(Rights)
metadata.only
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