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  3. Latent Class Analysis Identifies Four Distinct Patient Deprescribing Typologies Among Older Adults in Four Countries.
 

Latent Class Analysis Identifies Four Distinct Patient Deprescribing Typologies Among Older Adults in Four Countries.

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BORIS DOI
10.48620/85912
Date of Publication
January 17, 2025
Publication Type
Article
Division/Institute

Institute of General ...

Author
Weir, Kristie Rebecca
Institute of General Practice and Primary Care (BIHAM)
Marshall, Vincent D
Vordenberg, Sarah E
Subject(s)

600 - Technology::610...

Series
Innovation in Aging
ISSN or ISBN (if monograph)
2399-5300
Publisher
Oxford University Press
Language
English
Publisher DOI
10.1093/geroni/igaf002
PubMed ID
40008009
Uncontrolled Keywords

Attitudes

Deprescription

Health care communica...

Medicine

Patient preferences

Description
Background And Objectives
Polypharmacy, the concurrent use of multiple medicines, is a growing concern among older adults and those with chronic conditions. Deprescribing through dose reduction or discontinuing selected medicines is a strategy for reducing medicine-related harm. The Patient Deprescribing Typology was developed using qualitative methods to describe the varying factors that are important to older adults when they consider deprescribing. The objective of this study was to use quantitative methods to define distinct classes of older adults via the Patient Deprescribing Typology.Research Design And Methods
This study used a cross-sectional experimental design in which data was collected via an online survey from participants 65 years and older in Australia, the Netherlands, the United Kingdom, and the United States. A latent class analysis was performed using the 4-item Patient Deprescribing Typology that collected data about the beliefs about the importance of medicines, how older adults learn about medicines, medicine decision-making preferences, and attitudes towards stopping medicines.Results
Older adults (n = 2,250) were a median of 70 years and 2-thirds reported that their highest level of education was an associate's degree or trade school or less. We identified 4 distinct Patient Deprescribing Typology classes: Class 1 "Trusts their doctor" (41.6%), Class 2 "Makes own decisions" (30.2%), Class 3 "Avoids deprescribing" (15.5%), and Class 4 'Medicines not important' (12.7%).Discussion And Implications
Older adults report diverse perspectives about deprescribing, emphasizing the need for tailored communication strategies in clinical settings. Additional research is needed to examine older adults' preferences in real-world contexts to refine and improve deprescribing interventions.Clinical Trial Registration
NCT04676282.
Handle
https://boris-portal.unibe.ch/handle/20.500.12422/206114
Funding(s)
Swiss Government Excellence Scholarship
Swiss National Science Foundation
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FileFile TypeFormatSizeLicensePublisher/Copright statementContent
igaf002.pdftextAdobe PDF848.37 KBAttribution (CC BY 4.0)publishedOpen
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