Fast and user-friendly multi-spectra Mueller matrix polarimeter for fresh tissue biopsy imaging
Publisher DOI
Abstract
Mueller Matrix polarimetry (MMP) characterizes changes in light polarization after interacting with a medium, providing insights into tissue microstructure. Combined with multispectral (MS) imaging cameras, MS-MMP offers a novel way to quickly and safely acquire tissue surface information. Machine learning methodologies enable new diagnostic methods by automating tasks on fresh tissue biopsies, though this requires extensive and diverse data. To achieve this, we propose a user-friendly MS-MMP imager with a simple interface and fast acquisition time operated by laboratory technicians and residents. We show that our system, when operated by laboratory staff over several months, yields highquality data in large amounts and with positive feedback of its inclusion in a clinically compliant workflow. This positive outcome is promising for such systems to be used for large data collection initiatives.
Date Issued
2025-09-01
Publication Type
Article
Language(s)
en
Author(s)
Additional Credits
Journal
Current Directions in Biomedical Engineering
Publisher
De Gruyter
ISSN
2364-5504
Access(Rights)
open.access