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  3. Scaffold and organism hopping with chemical probes.
 

Scaffold and organism hopping with chemical probes.

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BORIS DOI
10.7892/boris.133492
Publisher DOI
10.1038/s41589-019-0275-9
PubMed ID
30992560
Description
Chemical probes that irreversibly inhibit protein function may be used across species to discover proteins. Combining phenotypic screening and activity-based protein profiling, a new study uncovers a discrete lipid signaling pathway regulating lifespan in the worm Caenorhabditis elegans.
Date of Publication
2019-05
Publication Type
Article
Subject(s)
500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health
Language(s)
en
Contributor(s)
Gertsch, Jürg
Institut für Biochemie und Molekulare Medizin (IBMM)
Additional Credits
Institut für Biochemie und Molekulare Medizin (IBMM)
Series
Nature chemical biology
Publisher
Springer Nature
ISSN
1552-4469
Access(Rights)
restricted
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