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  3. The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML
 

The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML

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Publisher DOI
10.1038/sj.bjc.6605751
PubMed ID
20628397
Description
CCAAT/enhancer-binding protein-alpha (CEBPA) is crucial for normal granulopoiesis and is frequently disrupted in acute myeloid leukaemia (AML). Increasing evidence suggests that CEBPA exerts its effects, in parts, by regulating specific microRNAs (miRNAs), as previously shown for miR-223. The aim of this study was to investigate the genome-wide pattern of miRNAs regulated by CEBPA in myeloid cells.
Date of Publication
2010
Publication Type
Article
Language(s)
en
Contributor(s)
Eyholzer, M
Schmid, S
Wilkens, L
Müller, Beatrice Ursula
Clinic of General Internal Medicine
Pabst, Thomas Niklaus
Universitätsklinik für Medizinische Onkologie
Additional Credits
Clinic of General Internal Medicine
Universitätsklinik für Medizinische Onkologie
Series
British journal of cancer
Publisher
Nature Publishing Group
ISSN
0007-0920
Access(Rights)
metadata.only
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