Publication:
Respiratory-related leg movements and their relationship with periodic leg movements during sleep

cris.virtualsource.author-orcidd1550197-9259-47f5-a7fd-50791947f14a
cris.virtualsource.author-orcidd2ea7c53-aafa-48c7-aa35-0e8839cf881f
dc.contributor.authorManconi, Mauro
dc.contributor.authorZavalko, I.
dc.contributor.authorBassetti, Claudio L.A.
dc.contributor.authorColamartino, E.
dc.contributor.authorPons, M.
dc.contributor.authorFerri, R.
dc.date.accessioned2024-10-15T14:11:29Z
dc.date.available2024-10-15T14:11:29Z
dc.date.issued2014
dc.description.abstractSTUDY OBJECTIVES: To describe the time structure of leg movements (LM) in obstructive sleep apnea (OSA) syndrome, in order to advance understanding of their clinical significance. LOCATION: Sleep Research Centre, Oasi Institute (IRCCS), Troina, Italy. SETTING: Sleep laboratory. PATIENTS: Eighty-four patients (16 females, 68 males, mean age 55.1 y, range 29-74 y). METHODS: Respiratory-related leg movements (RRLM) and those unrelated to respiratory events (NRLM) were examined within diagnostic polysomnograms alone and together for their distributions within the sleep period and for their periodicity. MEASUREMENTS AND RESULTS: Patients with OSA and RRLM exhibited more periodic leg movements in sleep (PLMS), particularly in NREM sleep. A gradual decrease in number of NRLM across the sleep period was observed in patients with RRLM. This pattern was less clear for RRLM. Frequency histograms of intermovement intervals of all LMs in patients with RRLM showed a prominent first peak at 4 sec, and a second peak at approximately 24 sec coincident with that of PLMS occurring in the absence of OSA. A third peak of lowest amplitude was the broadest with a maximum at approximately 42 sec. In patients lacking RRLM, NRLM were evident with a single peak at 2-4 sec. A stepwise linear regression analysis showed that, after controlling for a diagnosis of restless legs syndrome and apnea-hypopnea index, PLMS remained significantly associated with RRLM. CONCLUSION: The time structure of leg movements occurring in conjunction with respiratory events exhibit features of periodic leg movements in sleep occurring alone, only with a different and longer period. This brings into question the validity, both biologic and clinical, of scoring conventions with their a priori exclusion from consideration as periodic leg movements in sleep.
dc.description.noteNotes: Manconi, Mauro Zavalko, Irina Bassetti, Claudio L Colamartino, Elisabetta Pons, Marco Ferri, Raffaele Sleep. 2014 Mar 1;37(3):497-504. doi: 10.5665/sleep.3484. Custom 2: 3920315 Edition: 2014/03/04 Date: Mar Type of Work: Research Support, Non-U.S. Gov't
dc.description.numberOfPages8
dc.description.sponsorshipDekanat der Medizinischen Fakultät, Lehraufträge Insel
dc.description.sponsorshipUniversitätsklinik für Neurologie
dc.identifier.doi10.7892/boris.54204
dc.identifier.pmid24587572
dc.identifier.publisherDOI10.5665/sleep.3484
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/124543
dc.language.isoen
dc.publisherAmerican Academy of Sleep Medicine
dc.relation.ispartofSleep
dc.relation.issn0161-8105
dc.relation.organizationDCD5A442BAE0E17DE0405C82790C4DE2
dc.subject.ddc600 - Technology::610 - Medicine & health
dc.titleRespiratory-related leg movements and their relationship with periodic leg movements during sleep
dc.typearticle
dspace.entity.typePublication
dspace.file.typetext
oaire.citation.endPage504
oaire.citation.issue3
oaire.citation.startPage497
oaire.citation.volume37
oairecerif.author.affiliationDekanat der Medizinischen Fakultät, Lehraufträge Insel
oairecerif.author.affiliationUniversitätsklinik für Neurologie
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unibe.description.ispublishedpub
unibe.eprints.legacyId54204
unibe.journal.abbrevTitleSLEEP
unibe.refereedTRUE
unibe.subtype.articlejournal

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