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  3. 7T MRI as a powerful tool to detect small and medium size vessel CNS vasculitis.
 

7T MRI as a powerful tool to detect small and medium size vessel CNS vasculitis.

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Date of Publication
June 3, 2025
Publication Type
Article
Division/Institute

Institute of Diagnost...

Clinic of Neurology

Clinic of Rheumatolog...

Institute of Psycholo...

Author
Hoffmann, Angelika
Institute of Diagnostic and Interventional Neuroradiology
Almiri, William
Institute of Diagnostic and Interventional Neuroradiology
Mordasini, Pasquale
Institute of Diagnostic and Interventional Neuroradiology
Bähler, Alexandrine
Seiffge, David J.
Clinic of Neurology
Goeldlin, Martina B.orcid-logo
Clinic of Neurology
Jäger, Eugen
Institute of Diagnostic and Interventional Neuroradiology
Muresan, Ioan-Paul
Christ, Lisa
Clinic of Rheumatology and Immunology
Heldner, Mirjam R.orcid-logo
Clinic of Neurology
Wiest, Roland
Institute of Psychology
Institute of Diagnostic and Interventional Neuroradiology
Radojewski, Piotr
Institute of Diagnostic and Interventional Neuroradiology
Subject(s)

600 - Technology::610...

Series
American Journal of Neuroradiology
ISSN or ISBN (if monograph)
1936-959X
0195-6108
Publisher
American Society of Neuroradiology
Language
English
Publisher DOI
10.3174/ajnr.A8627
PubMed ID
39694614
Description
Imaging can help to diagnose CNS vasculitis. Yet so far, no imaging studies of CNS vasculitis at 7T are available. We share our experience of vessel wall imaging (VWI) at 7T in patients with suspected vasculitis. All included patients (n=45) underwent a clinically approved 7T MRI comprising high resolution arterial TOF angiography as well as high resolution VWI with T1SPACE and T1SE acquired pre-and post-contrast. 23 patients showed negative and 22 patients positive VWI at 7T. Ten out of 22 7T VWI positive cases were suggestive of vasculitis with 9 patients showing VWI of large and medium size vessels and one patient VWI of small vessels. Small vessel vasculitis was only depicted with 7T VWI, but not 3T VWI. Our work demonstrates that diagnosing CNS vasculitis, especially small vessel vasculitis, is feasible at 7T and highlights the potential of high field VWI encouraging further studies in this field.ABBREVIATIONS: FS= fat-saturated, SNR= signal-to-noise ratio, VWI= vessel wall imaging.
Handle
https://boris-portal.unibe.ch/handle/20.500.12422/194689
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