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  3. 7T MRI as a powerful tool to detect small and medium size vessel CNS vasculitis.

7T MRI as a powerful tool to detect small and medium size vessel CNS vasculitis.

Details
Publisher DOI
10.3174/ajnr.A8627
PubMed ID
39694614
Abstract
Imaging can help to diagnose CNS vasculitis. Yet so far, no imaging studies of CNS vasculitis at 7T are available. We share our experience of vessel wall imaging (VWI) at 7T in patients with suspected vasculitis. All included patients (n=45) underwent a clinically approved 7T MRI comprising high resolution arterial TOF angiography as well as high resolution VWI with T1SPACE and T1SE acquired pre-and post-contrast. 23 patients showed negative and 22 patients positive VWI at 7T. Ten out of 22 7T VWI positive cases were suggestive of vasculitis with 9 patients showing VWI of large and medium size vessels and one patient VWI of small vessels. Small vessel vasculitis was only depicted with 7T VWI, but not 3T VWI. Our work demonstrates that diagnosing CNS vasculitis, especially small vessel vasculitis, is feasible at 7T and highlights the potential of high field VWI encouraging further studies in this field.ABBREVIATIONS: FS= fat-saturated, SNR= signal-to-noise ratio, VWI= vessel wall imaging.
Date Issued
2025-06-03
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Language(s)
en
Author(s)
Hoffmann, Angelika  
Institute of Diagnostic and Interventional Neuroradiology  
Almiri, William  
Institute of Diagnostic and Interventional Neuroradiology  
Mordasini, Pasquale
Institute of Diagnostic and Interventional Neuroradiology  
Bähler, Alexandrine  
Seiffge, David J.  
Clinic of Neurology  
Goeldlin, Martina B.  orcid-logo
Clinic of Neurology  
Jäger, Eugen  
Institute of Diagnostic and Interventional Neuroradiology  
Muresan, Ioan-Paul
Christ, Lisa  
Clinic of Rheumatology and Immunology  
Heldner, Mirjam R.  orcid-logo
Clinic of Neurology  
Wiest, Roland  
Institute of Psychology  
Institute of Diagnostic and Interventional Neuroradiology  
Radojewski, Piotr  
Institute of Diagnostic and Interventional Neuroradiology  
Additional Credits
Institute of Diagnostic and Interventional Neuroradiology  
Clinic of Neurology  
Clinic of Rheumatology and Immunology  
Institute of Psychology  
Journal
American Journal of Neuroradiology
Publisher
American Society of Neuroradiology
ISSN
1936-959X
0195-6108
Related Collection(s)
MIDHOS - Metabolism I Inflammation I Digital Health I OSteology  
Access(Rights)
metadata.only
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