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  3. Effect of C-Clamp Application on Hemodynamic Instability in Polytrauma Victims with Pelvic Fracture.

Effect of C-Clamp Application on Hemodynamic Instability in Polytrauma Victims with Pelvic Fracture.

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DOI
10.48350/173232
Publisher DOI
10.3390/medicina58091291
PubMed ID
36143972
Abstract
Background and Objectives: C-clamp application may reduce mortality in patients with unstable pelvic fractures and hemodynamic instability. Decreasing C-clamp use over the past decades may have resulted from concerns about its effectiveness and safety. The purpose of this study was to document effective hemodynamic stabilization after C-clamp application by means of vital parameters (primary outcome parameter), and the subsequent effect on metabolic indices and volume management (secondary outcome parameters). Materials and Methods: C-clamp application was performed between 2014 and 2021 for n = 13 patients (50 ± 18 years) with unstable pelvic fractures and hemodynamic instability. Vital parameters, metabolic indices, volume management, and the correlation of factors and potential changes were analyzed. Results: After C-clamp application, increases were measured in systolic blood pressure (+15 mmHg; p = 0.0284) and mean arterial pressure (+12 mmHg; p = 0.0157), and a reduction of volume requirements (p = 0.0266) and bolus vasoactive medication needs (p = 0.0081) were observed. The earlier C-clamp application was performed, the greater the effect (p < 0.05; r > 0.6). Heart rate, shock index, and end-tidal CO2 were not significantly altered. The extent of base deficit, hemoglobin, and lactate did not correlate with changes in vital parameters. Conclusions: In the majority of hemodynamically unstable trauma patients not responding to initial fluid resuscitation and severe pelvic fracture, early C-clamp application had an additive effect on hemodynamic stabilization and reduction in volume substitution. Based on these findings, there is still a rationale for considering early C-clamp stabilization in this group of severely injured patients.
Date Issued
2022-09-16
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Subjects
emergency management hemodynamic instability pelvic C-clamp pelvic ring fracture
Language(s)
en
Author(s)
Gewiess, Jan  
Universitätsklinik für Orthopädische Chirurgie und Traumatologie  
Lüdi, Markus  
Universitätsklinik für Anästhesiologie und Schmerztherapie  
Schnüriger, Beat  
Universitätsklinik für Viszerale Chirurgie und Medizin, Viszeral- und Transplantationschirurgie  
Tosounidis, Theodoros Hercules
Keel, Marius  
Universitätsklinik für Orthopädische Chirurgie und Traumatologie  
Bastian, Johannes Dominik  
Universitätsklinik für Orthopädische Chirurgie und Traumatologie  
Additional Credits
Universitätsklinik für Orthopädische Chirurgie und Traumatologie  
Universitätsklinik für Viszerale Chirurgie und Medizin, Viszeral- und Transplantationschirurgie  
Universitätsklinik für Anästhesiologie und Schmerztherapie  
Journal
Medicina
Publisher
MDPI
ISSN
1648-9144
Access(Rights)
open.access
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