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Sustainability of vaginal estrogens for genitourinary syndrome of menopause - a systematic review.

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cris.virtualsource.author-orcid5bab78eb-4839-47b7-b411-14a35b086e55
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cris.virtualsource.author-orcid3f1d16b7-ad11-4134-bff6-9ad003d6de4f
dc.contributor.authorWeidlinger, Susanna
dc.contributor.authorSchmutz, C
dc.contributor.authorJanka, Heidrun Ilonka
dc.contributor.authorGruetter, C
dc.contributor.authorStute, Petra
dc.date.accessioned2024-10-07T05:44:47Z
dc.date.available2024-10-07T05:44:47Z
dc.date.issued2021-12
dc.description.abstractGenitourinary syndrome of menopause (GSM) is a highly prevalent, not self-limiting condition displaying a major negative impact on sexual function and emotional well-being. Various non-hormonal and hormonal treatment options are available. Many women consider GSM treatment to be a short-term interval cure rather than a long-term or lifelong treatment. The aim of this systematic literature search was to assess the sustainability of vaginal estrogens for GSM treatment after treatment cessation. We found that objective GSM signs mostly deteriorated within approximately 4 weeks after vaginal estrogen treatment cessation, while vaginal estrogens had a more sustainable impact on subjective GSM symptoms up to 3-6 months. However, overall, scientific evidence on sustainability of vaginal estrogens was low. Thus, GSM treatment should not be considered a short-term interval cure but long-term therapy. Further studies in an internationally harmonized setting (Core Outcomes in Menopause [COMMA]) are needed.
dc.description.numberOfPages9
dc.description.sponsorshipUniversitätsbibliothek Bern, Bibliothek Medizin
dc.description.sponsorshipUniversitätsklinik für Frauenheilkunde
dc.identifier.doi10.48350/163892
dc.identifier.pmid33709861
dc.identifier.publisherDOI10.1080/13697137.2021.1891218
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/59593
dc.language.isoen
dc.publisherInforma Healthcare
dc.relation.ispartofClimacteric
dc.relation.issn1369-7137
dc.relation.organizationDCD5A442BBB1E17DE0405C82790C4DE2
dc.relation.organizationDCD5A442C056E17DE0405C82790C4DE2
dc.subjectGenitourinary syndrome of menopause sustainability systematic review vaginal estrogens
dc.subject.ddc000 - Computer science, knowledge & systems::020 - Library & information sciences
dc.subject.ddc600 - Technology::610 - Medicine & health
dc.titleSustainability of vaginal estrogens for genitourinary syndrome of menopause - a systematic review.
dc.typearticle
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oaire.citation.endPage559
oaire.citation.issue6
oaire.citation.startPage551
oaire.citation.volume24
oairecerif.author.affiliationUniversitätsklinik für Frauenheilkunde
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oairecerif.author.affiliationUniversitätsbibliothek Bern, Bibliothek Medizin
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oairecerif.author.affiliationUniversitätsklinik für Frauenheilkunde
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unibe.date.licenseChanged2022-01-07 19:21:05
unibe.description.ispublishedpub
unibe.eprints.legacyId163892
unibe.journal.abbrevTitleCLIMACTERIC
unibe.refereedTRUE
unibe.subtype.articlereview

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