Publication:
Directional local field potentials: A tool to optimize deep brain stimulation.

cris.virtualsource.author-orcid75cafddf-7a30-42b6-b2ae-da9ecdde9dac
cris.virtualsource.author-orcid102de81f-2b9c-4515-987d-26857ece40f5
cris.virtualsource.author-orcid5d7b444a-1679-46d0-a090-1f49981c7bee
cris.virtualsource.author-orcid5f30e723-258d-43e2-964a-3508a2d39d0b
cris.virtualsource.author-orcid3e4cd27e-3f1f-4190-ac87-f7f20c0b687b
cris.virtualsource.author-orcid68dc9e66-a848-430d-9e01-f43f30b18514
cris.virtualsource.author-orcidf65fd4b6-76c4-4787-908d-19ff160585a6
cris.virtualsource.author-orcid346186a4-a537-4773-8e5e-689017a507e1
datacite.rightsopen.access
dc.contributor.authorTinkhauser, Gerd
dc.contributor.authorPogosyan, Alek
dc.contributor.authorDebove, Ines
dc.contributor.authorNowacki, Andreas
dc.contributor.authorShah, Syed Ahmar
dc.contributor.authorSeidel, Kathleen
dc.contributor.authorTan, Huiling
dc.contributor.authorBrittain, John-Stuart
dc.contributor.authorPetermann, Katrin
dc.contributor.authordi Biase, Lazzaro
dc.contributor.authorOertel, Markus Florian
dc.contributor.authorPollo, Claudio
dc.contributor.authorBrown, Peter
dc.contributor.authorSchüpbach, Michael
dc.date.accessioned2024-10-25T13:11:45Z
dc.date.available2024-10-25T13:11:45Z
dc.date.issued2018-01
dc.description.abstractBACKGROUND Although recently introduced directional DBS leads provide control of the stimulation field, programing is time-consuming. OBJECTIVES Here, we validate local field potentials recorded from directional contacts as a predictor of the most efficient contacts for stimulation in patients with PD. METHODS Intraoperative local field potentials were recorded from directional contacts in the STN of 12 patients and beta activity compared with the results of the clinical contact review performed after 4 to 7 months. RESULTS Normalized beta activity was positively correlated with the contact's clinical efficacy. The two contacts with the highest beta activity included the most efficient stimulation contact in up to 92% and that with the widest therapeutic window in 74% of cases. CONCLUSION Local field potentials predict the most efficient stimulation contacts and may provide a useful tool to expedite the selection of the optimal contact for directional DBS. © 2017 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.
dc.description.numberOfPages6
dc.description.sponsorshipUniversitätsklinik für Neurologie
dc.description.sponsorshipUniversitätsklinik für Neurochirurgie
dc.identifier.doi10.7892/boris.107258
dc.identifier.pmid29150884
dc.identifier.publisherDOI10.1002/mds.27215
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/155737
dc.language.isoen
dc.publisherWiley-Blackwell
dc.relation.ispartofMovement disorders
dc.relation.issn0885-3185
dc.relation.organizationDCD5A442BAE0E17DE0405C82790C4DE2
dc.relation.organizationDCD5A442C057E17DE0405C82790C4DE2
dc.subjectDBS programming Parkinson's disease deep brain stimulation directional leads local field potentials
dc.subject.ddc600 - Technology::610 - Medicine & health
dc.titleDirectional local field potentials: A tool to optimize deep brain stimulation.
dc.typearticle
dspace.entity.typePublication
dspace.file.typetext
oaire.citation.endPage164
oaire.citation.issue1
oaire.citation.startPage159
oaire.citation.volume33
oairecerif.author.affiliationUniversitätsklinik für Neurologie
oairecerif.author.affiliationUniversitätsklinik für Neurologie
oairecerif.author.affiliationUniversitätsklinik für Neurochirurgie
oairecerif.author.affiliationUniversitätsklinik für Neurochirurgie
oairecerif.author.affiliationUniversitätsklinik für Neurologie
oairecerif.author.affiliationUniversitätsklinik für Neurochirurgie
oairecerif.author.affiliationUniversitätsklinik für Neurochirurgie
oairecerif.author.affiliationUniversitätsklinik für Neurologie
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unibe.date.licenseChanged2019-10-26 00:31:01
unibe.description.ispublishedpub
unibe.eprints.legacyId107258
unibe.journal.abbrevTitleMOVEMENT DISORD
unibe.refereedtrue
unibe.subtype.articlejournal

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