Fertility Treatment After Fertility Preservation Therapies

As soon as it is medically justifiable, cryopreserved gametes or the cryopreserved gonadal tissue can be thawed. Sperm are used either for intrauterine insemination or IVF/ICSI therapy. The birth rate per patient is approximately 50%. If oocytes had been cryopreserved, the birth rates are about 35% if all frozen oocytes are transferred after fertilization. Ovarian tissue is transplanted orthotopically, which leads to birth rates of approximately 25% according to current data. If IVF/ICSI therapy is carried out treatment require modifications due to the frequently very low ovarian reserve after gonadotoxic therapy.