Postmortem examination and immunohistochemical and bacteriologic analyses on a free-ranging European red squirrel (Sciurus vulgaris) revealed a systemic infection with Francisella tularensis. Genome sequencing and single-nucleotide polymorphism (SNP) analysis were consistent with F. tularensis subs. holarctica clade B.45. Tularemia has not previously been reported in this species.
