Stereoselective synthesis of a monocyclic peloruside a analogue
Publisher DOI
PubMed ID
20141163
Abstract
The stereoselective synthesis of the monocyclic peloruside A analogue 4 has been achieved, following a new efficient approach for the introduction of the side chain, involving a late-stage addition of vinyl lithium species 7a to aldehyde 8. Further key steps are a highly diastereoselective allyltitanation reaction and a RCM-based macrocyclization.
Date Issued
2010
Publication Type
Article
Language(s)
en
Author(s)
Wullschleger, Christoph W | |
Altmann, Karl-Heinz |
Additional Credits
Journal
Organic letters
Publisher
American Chemical Society
ISSN
1523-7060
Access(Rights)
metadata.only