Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway

Publisher DOI
PubMed ID
20470887
Description
The proliferation signal inhibitors (PSIs) sirolimus (SRL) and everolimus (ERL) often induce proteinuria due to glomerular but also tubular dysfunction in transplant patients. The beneficial effect of angiotensin converting enzyme inhibitors (ACE-I) and angiotensin II (Ang II) type 1 receptor blockers (ARB) has been reported.
Date of Publication
2010
Publication Type
Article
Language(s)
en
Contributor(s)
Bieri, Michael
Ligeti, Nathalie
Farkas, Anikó
Additional Credits
Series
Transplant immunology
Publisher
Elsevier
ISSN
0966-3274
Access(Rights)
metadata.only
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