Gender-specific elimination of continuous-infusional 5-fluorouracil in patients with gastrointestinal malignancies: results from a prospective population pharmacokinetic study

BORIS DOI
Publisher DOI
PubMed ID
23139054
Description
This study was initiated to assess the quantitative impact of patient anthropometrics and dihydropyrimidine dehydrogenase (DPYD) mutations on the pharmacokinetics (PK) of 5-fluorouracil (5FU) and to explore limited sampling strategies of 5FU.
Date of Publication
2013
Publication Type
Article
Subject(s)
600 - Technology::610 - Medicine & health
500 - Science::570 - Life sciences; biology
500 - Science::540 - Chemistry
Language(s)
en
Contributor(s)
Mueller, F
Köberle, D
Pfister, B
Krähenbühl, St
Joerger, M
Additional Credits
Universitätsinstitut für Klinische Chemie (UKC)
Departement für Chemie und Biochemie (DCB)
Series
Cancer chemotherapy and pharmacology
Publisher
Springer
ISSN
0344-5704
Access(Rights)
open.access
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