Publication:
Impact of Type 1 Diabetes Mellitus on Bone Health in Children

cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtual.author-orcid#PLACEHOLDER_PARENT_METADATA_VALUE#
cris.virtualsource.author-orcid9ed9dc66-fad2-4efd-8465-64a049d4da03
cris.virtualsource.author-orcide21029a1-fd88-4597-8e1f-25b4dc892347
dc.contributor.authorJanner, Marco
dc.contributor.authorSaner, Christoph
dc.date.accessioned2024-10-09T16:50:42Z
dc.date.available2024-10-09T16:50:42Z
dc.date.issued2022
dc.description.abstractThis paper gives an overview of the impact of type 1 diabetes on bone health in children and adolescents. Firstly, we analyse studies using dual X-ray absorptiometry to assess bone mineral content and bone mineral density. Then, we discuss modern, non-invasive techniques including peripheral quantitative computer tomography (pQCT) and high-resolution pQCT for the detailed assessment of bone health aspects including bone mass, bone geometry, bone microarchitecture, and bone strength. Thereafter, we explore some of the mechanisms that are responsible for diabetic bone disease in children, like low bone turnover and high sclerostin levels. Finally, we summarize some of the evidence for the importance of microvascular disease in the pathophysiology of diabetic bone disease
dc.description.numberOfPages10
dc.description.sponsorshipUniversitätsklinik für Kinderheilkunde
dc.identifier.doi10.48350/165416
dc.identifier.pmid34937025
dc.identifier.publisherDOI10.1159/000521627
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/67386
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofHormone research in paediatrics
dc.relation.issn1663-2818
dc.relation.organizationDCD5A442BADAE17DE0405C82790C4DE2
dc.relation.organizationDCD5A442C248E17DE0405C82790C4DE2
dc.relation.organizationDCD5A442C266E17DE0405C82790C4DE2
dc.subject.ddc600 - Technology::610 - Medicine & health
dc.titleImpact of Type 1 Diabetes Mellitus on Bone Health in Children
dc.typearticle
dspace.entity.typePublication
dspace.file.typetext
oaire.citation.endPage214
oaire.citation.issue3
oaire.citation.startPage205
oaire.citation.volume95
oairecerif.author.affiliationUniversitätsklinik für Kinderheilkunde
oairecerif.author.affiliationUniversitätsklinik für Kinderheilkunde
oairecerif.author.affiliation2Department for BioMedical Research, Forschungsgruppe Endokrinologie / Diabetologie / Metabolik (Pädiatrie)
oairecerif.author.affiliation2Department for BioMedical Research, Forschungsgruppe Endokrinologie / Diabetologie / Metabolik (Pädiatrie)
oairecerif.author.affiliation3#PLACEHOLDER_PARENT_METADATA_VALUE#
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oairecerif.author.affiliation4#PLACEHOLDER_PARENT_METADATA_VALUE#
oairecerif.author.affiliation4#PLACEHOLDER_PARENT_METADATA_VALUE#
unibe.contributor.rolecreator
unibe.contributor.rolecreator
unibe.date.licenseChanged2022-03-02 14:26:42
unibe.description.ispublishedpub
unibe.eprints.legacyId165416
unibe.journal.abbrevTitleHorm Res Paediatr
unibe.refereedTRUE
unibe.subtype.articlereview

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