Tricuspid valve disease: updates on diagnostic imaging and intervention.

DOI
Publisher DOI
PubMed ID
41478883
Abstract
Tricuspid regurgitation is associated with an increased risk of hospitalization and death. Many patients with severe tricuspid regurgitation are unable to undergo surgical intervention owing to prohibitive technical or clinical risk. The past two decades has seen an outburst of technological advances in the field of transcatheter tricuspid technologies, with numerous randomized, controlled trials assessing the safety and efficacy of various repair and replacement therapies for tricuspid regurgitation. However, crucial knowledge gaps persist, particularly in areas such as patient selection, anatomical eligibility and the haemodynamic effects of device implantation. In this Review, we outline the anatomical features of the tricuspid valve and the haemodynamic consequences of tricuspid regurgitation, and we summarize the imaging modalities used for diagnosis and management. Furthermore, we detail the current guideline-directed medical therapy for tricuspid regurgitation, as well as valve repair and replacement surgical procedures being tested in clinical trials. Finally, we highlight future technological innovations that promise to optimize diagnosis, patient selection and the device development process.
Date Issued
2026-06
Publication Type
Article
Language(s)
en
Author(s)
Grapsa, Julia
Zancanaro, Edoardo
Rommel, Karl Philipp
Weber, Lukas
Coisne, Augustin
Estevez-Loureiro, Rodrigo
Delgado, Victoria
Sitges, Marta
Enriquez-Sarano, Maurice
Fam, Neil
Cristell, Nicole
Latib, Azeem
Piazza, Nicolo
Lurz, Philipp
Modine, Thomas
Hausleiter, Jörg
Hahn, Rebecca T
Leon, Martin B
Granada, Juan F
Additional Credits
Journal
Nature Reviews Cardiology
Publisher
Nature Research
ISSN
1759-5010
1759-5002
Access(Rights)
restricted
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