Osteoblast proliferation and differentiation on a barrier membrane in combination with BMP2 and TGFβ1
Publisher DOI
PubMed ID
22669486
Abstract
Bioresorbable collagen membranes are routinely utilized in guided bone regeneration to selectively direct the growth and repopulation of bone cells in areas of insufficient volume. However, the exact nature by which alveolar osteoblasts react to barrier membranes as well as the effects following the addition of growth factors to the membranes are still poorly understood. The objective of the present study was therefore to investigate the effect of a bioresorbable collagen membrane soak-loaded in growth factors bone morphogenetic protein 2 (BMP2) or transforming growth factor β1 (TGFβ1) on osteoblast adhesion, proliferation, and differentiation.
Date Issued
2013
Publication Type
Article
Subject(s)
Language(s)
en
Author(s)
Journal
Clinical oral investigations
Publisher
Springer-Verlag
ISSN
1432-6981
Access(Rights)
open.access