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  3. Endovascular treatment of tandem occlusions in vertebrobasilar stroke: technical aspects and outcome compared with isolated basilar artery occlusion.
 

Endovascular treatment of tandem occlusions in vertebrobasilar stroke: technical aspects and outcome compared with isolated basilar artery occlusion.

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BORIS DOI
10.7892/boris.131168
Publisher DOI
10.1136/neurintsurg-2019-014825
PubMed ID
31113810
Description
BACKGROUND AND PURPOSE

Acute basilar artery occlusion (BAO) is a devastating disease with a high rate of mortality and morbidity, and early recanalization is crucial to achieve a good prognosis. The best treatment strategy for BAO combined with a proximal stenosis (tandem occlusion) is not yet clear. Our study aimed to evaluate whether and how vertebrobasilar tandem occlusions can be treated effectively and safely compared with isolated BAO.

MATERIALS AND METHODS

Fifty-two patients with acute vertebrobasilar occlusive stroke treated with mechanical thrombectomy were identified in a prospective database from March 2010 to September 2016. We retrospectively analysed the clinical, technical, and functional outcomes of the patients.

RESULTS

Of the 52 patients, 15 presented with a tandem occlusion, 14 with a single intracranial occlusion due to an underlying stenosis, and 23 with a single embolic BAO. Successful recanalization was achieved in all of the patients with tandem occlusions (modified Thrombolysis in Cranial Infarction 2b/3) and in 35 of 37 patients with a single BAO (with and without stenosis). A favourable outcome was achieved (modified Rankin Scale ≤2) in 8 of the 15 patients with a tandem occlusion compared with 4 of the 14 patients with a single BAO with underlying stenosis and 5 of the 23 patients with isolated embolic BAO (p=0.18).

CONCLUSIONS

We suggest that endovascular treatment of vertebrobasilar tandem occlusions is safe and feasible, with a high rate of good outcome.
Date of Publication
2020-01
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Keyword(s)
artery stroke technique
Language(s)
en
Contributor(s)
Piechowiak, Eike Immo
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie
Kaesmacher, Johannes
Universitätsklinik für Neurologie
Universitätsinstitut für Diagnostische, Interventionelle und Pädiatrische Radiologie
Zibold, Felix
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie
Dobrocky, Tomas
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie
Mosimann, Pascal John
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie
Jung, Simon
Universitätsklinik für Neurologie
Fischer, Urs Martin
Universitätsklinik für Neurologie
Arnold, Marcel
Universitätsklinik für Neurologie
Bellwald, Sebastian
Universitätsklinik für Neurologie
Heldner, Mirjam Rachelorcid-logo
Universitätsklinik für Neurologie
Gralla, Jan
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie
Mordasini, Pasquale Renato
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie
Additional Credits
Universitätsinstitut für Diagnostische und Interventionelle Neuroradiologie
Universitätsklinik für Neurologie
Series
Journal of neurointerventional surgery
Publisher
BMJ Publishing Group
ISSN
1759-8486
Access(Rights)
restricted
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