Apoptosis in disease: about shortage and excess.
Publisher DOI
PubMed ID
14585078
Abstract
The death of cells by apoptosis is a fundamental event in development and the maintenance of cell homoeostasis. The other side of the coin, however, is that excessive cell death by apoptosis or the lack of apoptosis is often the driving force of many diseases. Whereas reduced apoptosis sensitivity is a basic characteristic of many tumour cells, accelerated tissue cell death and loss of tissue functions is the underlying cause of many auto-immune and inflammatory diseases.
Date Issued
2003
Publication Type
Article
Language(s)
en
Additional Credits
Journal
Essays in biochemistry
Publisher
Portland Press
ISSN
1744-1358
Access(Rights)
metadata.only