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  3. HIV-Positive-to-HIV-Positive Liver Transplantation.

HIV-Positive-to-HIV-Positive Liver Transplantation.

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DOI
10.7892/boris.93403
Publisher DOI
10.1111/ajt.13824
PubMed ID
27109874
Abstract
Most countries exclude human immunodeficiency virus (HIV)-positive patients from organ donation because of concerns regarding donor-derived HIV transmission. The Swiss Federal Act on Transplantation has allowed organ transplantation between HIV-positive donors and recipients since 2007. We report the successful liver transplantation from an HIV-positive donor to an HIV-positive recipient. Both donor and recipient had been treated for many years with antiretroviral therapy and harbored multidrug-resistant viruses. Five months after transplantation, HIV viremia remains undetectable. This observation supports the inclusion of appropriate HIV-positive donors for transplants specifically allocated to HIV-positive recipients.
Date Issued
2016-08
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Subjects
clinical research/practice
•
ethics and public policy
•
immune deficiency
•
infectious disease
•
patient safety
Language(s)
en
Author(s)
Calmy, A
van Delden, C
Giostra, E
Junet, C
Rubbia Brandt, L
Yerly, S
Chave, J-P
Samer, C
Elkrief, L
Vionnet, J
Beldi, Guido  
Universitätsklinik für Viszerale Chirurgie und Medizin, Viszeral- und Transplantationschirurgie  
Departement Klinische Forschung, Forschungsgruppe Viszeralchirurgie  
Huynh-Do, Uyen  
Universitätsklinik für Nephrologie, Hypertonie und Klinische Pharmakologie  
Departement Klinische Forschung, Forschungsgruppe Nephrologie / Hypertonie  
Stirnimann, Guido  
Universitätsklinik für Viszerale Chirurgie und Medizin, Hepatologie  
Departement Klinische Forschung, Hepatologie Forschung  
Berney, T
Swiss Transplant Cohort Study, STCS
Additional Credits
Universitätsklinik für Viszerale Chirurgie und Medizin, Viszeral- und Transplantationschirurgie  
Universitätsklinik für Nephrologie, Hypertonie und Klinische Pharmakologie  
Departement Klinische Forschung, Forschungsgruppe Viszeralchirurgie  
Universitätsklinik für Viszerale Chirurgie und Medizin, Hepatologie  
Departement Klinische Forschung, Forschungsgruppe Nephrologie / Hypertonie  
Departement Klinische Forschung, Hepatologie Forschung  
Journal
American journal of transplantation
Publisher
Wiley-Blackwell
ISSN
1600-6135
Access(Rights)
restricted
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