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  3. Accuracy and reproducibility of aortic annulus sizing using a dedicated three-dimensional computed tomography reconstruction tool in patients evaluated for transcatheter aortic valve replacement

Accuracy and reproducibility of aortic annulus sizing using a dedicated three-dimensional computed tomography reconstruction tool in patients evaluated for transcatheter aortic valve replacement

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DOI
10.7892/boris.41943
PubMed ID
24273249
Abstract
Aims: To evaluate the accuracy and reproducibility of aortic annulus sizing using a multislice computed tomography (MSCT) based aortic root reconstruction tool compared with conventional imaging among patients evaluated for transcatheter aortic valve replacement (TAVR). Methods and results: Patients referred for TAVR underwent standard preprocedural assessment of aortic annulus parameters using MSCT, angiography and transoesophageal echocardiography (TEE). Three-dimensional (3-D) reconstruction of MSCT images of the aortic root was performed using 3mensio (3mensio Medical Imaging BV, Bilthoven, The Netherlands), allowing for semi-automated delineation of the annular plane and assessment of annulus perimeter, area, maximum, minimum and virtual diameters derived from area and perimeter (aVD and pVD). A total of 177 patients were enrolled. We observed a good inter-observer variability of 3-D reconstruction assessments with concordance coefficients for agreement of 0.91 (95% CI: 0.87-0.93) and 0.91 (0.88-0.94) for annulus perimeter and area assessments, respectively. 3-D derived pVD and aVD correlated very closely with a concordance coefficient of 0.97 (0.96-0.98) with a mean difference of 0.5±0.3 mm (pVD-aVD). 3-D derived pVD showed the best, but moderate concordance with diameters obtained from coronal MSCT (0.67, 0.56-0.75; 0.3±1.8 mm), and the lowest concordance with diameters obtained from TEE (0.42, 0.31-0.52; 1.9±1.9 mm). Conclusions: MSCT-based 3-D reconstruction of the aortic annulus using the 3mensio software enables accurate and reproducible assessment of aortic annulus dimensions.
Date Issued
2014-07-20
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Language(s)
en
Author(s)
Stortecky, Stefan  
Universitätsklinik für Kardiologie  
Heg, Dierik Hans  
Departement Klinische Forschung, Core Facility, Clinical Trials Unit (CTU) Bern  
Glökler, Steffen  
Universitätsklinik für Kardiologie  
Wenaweser, Peter Martin  
Universitätsklinik für Kardiologie  
Windecker, Stephan  
Universitätsklinik für Kardiologie  
Büllesfeld, Lutz  
Universitätsklinik für Kardiologie  
Additional Credits
Universitätsklinik für Kardiologie  
Departement Klinische Forschung, Core Facility, Clinical Trials Unit (CTU) Bern  
Journal
EuroIntervention
Publisher
Europa Digital & Publishing
ISSN
1774-024X
Access(Rights)
open.access
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