[Subclinical hypothyroidism : should we still treat elderly patients? Clinical implications of a new trial in primary care].

DOI
PubMed ID
29489127
Abstract
Subclinical hypothyroidism, defined as an elevated level of thyrotropin hormone (TSH) and normal thyroxin, is more frequent in women and above 65 years old. This condition is associated with an increased cardiovascular risk, in particular with TSH > 10,0 mIU/L. Although overt hypothyroidism is rare (prevalence of 0,3 %), levothyroxine has become the most prescribed medication in the US, while its indications are still debated. The European-funded TRUST trial showed no improvement in Hypothyroid Symptoms and Tiredness scores among patients ≥ 65 years with subclinical hypothyroidism treated with levothyroxine, and no improvement in blood pressure, weight, muscle strength and cognition. The results of this study call for a revision of the current international recommendations on the treatment of subclinical hypothyroidism.
Date Issued
2018-02-28
Publication Type
Article
Subject(s)
Language(s)
fr
Author(s)
Collet, Tinh-Hai
Sykiotis, Gerasimos P
Blum, Manuel Raphael
Additional Credits
Journal
Revue médicale suisse
Publisher
Médecine & Hygiène
ISSN
0025-6749
Access(Rights)
restricted
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