Hemispheric lateralization of the corticostriatal glutamatergic system in the rat
Publisher DOI
PubMed ID
19626270
Abstract
Little is known about hemispheric lateralization of subcortical structures. Here, we show a higher expression of the subunit NR2A of the NMDA receptor mRNA in the striatum and of vGluT1 mRNA in the cingulate cortex, in the left hemisphere compared to the right one. This suggests a lateralization of the glutamatergic cortico-subcortical system, at the level of postsynaptic receptors as well as at the level of corticostriatal projections. Such lateralization could play a role in asymmetric diseases like Parkinson's disease.
Date Issued
2009
Publication Type
Article
Language(s)
en
Author(s)
Rebell, Dominik | |
Kaelin-Lang, Alain |
Additional Credits
Journal
Journal of neural transmission
Publisher
Springer Vienna
ISSN
0300-9564
Access(Rights)
open.access