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  3. Cerebral revascularization model in a swine

Cerebral revascularization model in a swine

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PubMed ID
16060257
Abstract
The purpose of this study was to analyze the suitability of the cerebral vasculature of the pig regarding a revascularization procedure. In two 60 kg pigs the femoral artery was exposed and canulated for selective angiography and interventional procedures. After the angiography, the pigs were brought to the animal OR for craniotomy and analysis of the intracranial cerebral arteries and the surgical exposure of the carotid arteries under the microscope. Angiography demonstrated the presence of a true internal-, external carotid artery and vertebral arteries. Both the vertebral and internal carotid arteries are feeding a rete mirabilis both at the cranial base and the cranio-cervical junction. At these sites further advancement of the angiography catheter was not possible. Out of these rete mirabilis, an intracranial carotid artery and an intracranial vertebral artery were formed, respectively. The intracranial cerebral vessels were of the dimension of 1 mm and less. The extracranial portion of the internal carotid artery was 2.5 mm of diameter. From these findings, we conclude that a direct cerebral revascularization procedure of the intracranial vessels is not possible in the swine. However, a global revascularization procedure on the extracranial portion of the internal carotid artery is thus feasible, both using a low- and high-flow anastamosis technique.
Date Issued
2005
Publication Type
Article
Language(s)
en
Author(s)
Reinert, Michael  
Universitätsklinik für Neurochirurgie  
Brekenfeld, C
Taussky, P
Andres, R
Barth, A
Seiler, R W
Additional Credits
Universitätsklinik für Neurochirurgie  
Journal
Acta neurochirurgica - supplementa
Publisher
Springer
ISSN
0065-1419
ISBN
16060257
Access(Rights)
metadata.only
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