Spinal MRI supporting myelopathic origin of early symptoms in unsuspected cobalamin deficiency
Publisher DOI
PubMed ID
12646757
Abstract
We report two patients with subjectively progressive sensory symptoms and gait disturbance due to cobalamin deficiency, but only slight or absent abnormalities on neurological examination. In both patients, spinal MRI provided evidence for a myelopathic origin of the symptoms, disclosing characteristic T(2) hyperintense signal alterations confined to the posterior columns of the cervical and thoracic spinal cord. The patients illustrate the early clinical presentation of subacute combined degeneration (SCD) with a sensory neuropathy starting with acroparesthesia and Lhermitte's sign. Furthermore, the diagnostic value of spinal MRI for early diagnosis of SCD with characteristic findings is highlighted.
Date Issued
2003
Publication Type
Article
Language(s)
en
Author(s)
Sturzenegger, Matthias |
Additional Credits
Journal
European neurology
Publisher
Karger
ISSN
0014-3022
ISBN
12646757
Access(Rights)
metadata.only