Detection and Differentiation of Intraretinal Hemorrhage in Spectral Domain Optical Coherence Tomography.
Publisher DOI
PubMed ID
25329527
Abstract
PURPOSE
The purpose of this study was to classify and detect intraretinal hemorrhage (IRH) in spectral domain optical coherence tomography (SD-OCT).
METHODS
Initially the presentation of IRH in BRVO-patients in SD-OCT was described by one reader comparing color-fundus (CF) and SD-OCT using dedicated software. Based on these established characteristics, the presence and the severity of IRH in SD-OCT and CF were assessed by two other masked readers and the inter-device and the inter-observer agreement were evaluated. Further the area of IRH was compared.
RESULTS
About 895 single B-scans of 24 eyes were analyzed. About 61% of SD-OCT scans and 46% of the CF-images were graded for the presence of IRH (concordance: 73%, inter-device agreement: k = 0.5). However, subdivided into previously established severity levels of dense (CF: 21.3% versus SD-OCT: 34.7%, k = 0.2), flame-like (CF: 15.5% versus SD-OCT: 45.5%, k = 0.3), and dot-like (CF: 32% versus SD-OCT: 24.4%, k = 0.2) IRH, the inter-device agreement was weak. The inter-observer agreement was strong with k = 0.9 for SD-OCT and k = 0.8 for CF. The mean area of IRH detected on SD-OCT was significantly greater than on CF (SD-OCT: 11.5 ± 4.3 mm(2) versus CF: 8.1 ± 5.5 mm(2), p = 0.008).
CONCLUSIONS
IRH seems to be detectable on SD-OCT; however, the previously established severity grading agreed weakly with that assessed by CF.
The purpose of this study was to classify and detect intraretinal hemorrhage (IRH) in spectral domain optical coherence tomography (SD-OCT).
METHODS
Initially the presentation of IRH in BRVO-patients in SD-OCT was described by one reader comparing color-fundus (CF) and SD-OCT using dedicated software. Based on these established characteristics, the presence and the severity of IRH in SD-OCT and CF were assessed by two other masked readers and the inter-device and the inter-observer agreement were evaluated. Further the area of IRH was compared.
RESULTS
About 895 single B-scans of 24 eyes were analyzed. About 61% of SD-OCT scans and 46% of the CF-images were graded for the presence of IRH (concordance: 73%, inter-device agreement: k = 0.5). However, subdivided into previously established severity levels of dense (CF: 21.3% versus SD-OCT: 34.7%, k = 0.2), flame-like (CF: 15.5% versus SD-OCT: 45.5%, k = 0.3), and dot-like (CF: 32% versus SD-OCT: 24.4%, k = 0.2) IRH, the inter-device agreement was weak. The inter-observer agreement was strong with k = 0.9 for SD-OCT and k = 0.8 for CF. The mean area of IRH detected on SD-OCT was significantly greater than on CF (SD-OCT: 11.5 ± 4.3 mm(2) versus CF: 8.1 ± 5.5 mm(2), p = 0.008).
CONCLUSIONS
IRH seems to be detectable on SD-OCT; however, the previously established severity grading agreed weakly with that assessed by CF.
Date Issued
2014-10-20
Publication Type
Article
Subject(s)
Subjects
Imaging
•
intraretinal blood
•
intraretinal hemorrhage
•
multimodal imaging
•
optical coherence tomography
•
retinal vein occlusion
Language(s)
en
Author(s)
Munk, Marion R | |
Dunavoelgyi, Roman | |
Baratsits, Magdalena | |
Matt, Gerlinde | |
Montuoro, Alessio | |
Buehl, Wolf | |
Schmidt-Erfurth, Ursula | |
Sacu, Stefan |
Journal
Current eye research
Publisher
Informa Healthcare
ISSN
0271-3683
Access(Rights)
metadata.only