Radiolabeled bicyclic somatostatin-based analogs: a novel class of potential radiotracers for SPECT/PET of neuroendocrine tumors
Publisher DOI
PubMed ID
20956465
Abstract
A variety of radiolabeled somatostatin analogs have been developed for targeting of somatostatin receptor (sst)-positive tumors. Bicyclic somatostatin-based radiopeptides have not been studied yet. Hypothesizing that the introduction of conformational constraints may lead to receptor subtype selectivity or may help to delineate structural features determining pansomatostatin potency, we developed and evaluated first examples of this new class of potential radiotracers for imaging or therapy of neuroendocrine tumors.
Date Issued
2010
Publication Type
Article
Language(s)
en
Author(s)
Fani, Melpomeni | |
Mueller, Andreas | |
Tamma, Maria-Luisa | |
Nicolas, Guillaume | |
Rink, Hans R | |
Maecke, Helmut R |
Additional Credits
Journal
Journal of nuclear medicine
Publisher
Society of Nuclear Medicine
ISSN
0161-5505
Access(Rights)
metadata.only