Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO).

DOI
Publisher DOI
PubMed ID
28391295
Abstract
The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy (with particular attention to brain metastases from non-small cell lung cancer, melanoma and breast and renal cancer), and supportive care.
Date Issued
2017-02-01
Publication Type
Article
Subject(s)
Subjects
brain metastases chemotherapy neuroimaging neuropathology stereotactic radiosurgery/stereotactic fractionated radiotherapy supportive care surgery targeted therapy whole-brain radiation therapy
Language(s)
en
Author(s)
Soffietti, Riccardo
Abacioglu, Ufuk
Baumert, Brigitta
Combs, Stephanie E
Kinhult, Sara
Kros, Johan M
Marosi, Christine
Metellus, Philippe
Radbruch, Alexander
Villa Freixa, Salvador S
Brada, Michael
Carapella, Carmine M
Preusser, Matthias
Le Rhun, Emilie
Rudà, Roberta
Tonn, Joerg C
Weller, Michael
Additional Credits
Journal
Neuro-Oncology
Publisher
Oxford University Press
ISSN
1523-5866
Access(Rights)
restricted
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