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  3. Targeting PI3KC2β impairs proliferation and survival in acute leukemia, brain tumours and neuroendocrine tumours
 

Targeting PI3KC2β impairs proliferation and survival in acute leukemia, brain tumours and neuroendocrine tumours

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PubMed ID
22843869
Description
Eight human catalytic phosphoinositide 3-kinase (PI3K) isoforms exist which are subdivided into three classes. While class I isoforms have been well-studied in cancer, little is known about the functions of class II PI3Ks.
Date of Publication
2012
Publication Type
Article
Language(s)
en
Contributor(s)
Boller, Danielle
Doepfner, Kathrin T
De Laurentiis, Angela
Guerreiro, Ana S
Marinov, Marin
Shalaby, Tarek
Depledge, Paul
Robson, Anthony
Saghir, Nahid
Hayakawa, Masahiko
Kaizawa, Hiroyuki
Koizumi, Tomonobu
Ohishi, Takahide
Fattet, Sarah
Delattre, Olivier
Schweri-Olac, Anelia
Höland, Katrin
Universitätsklinik für Kinderheilkunde
Grotzer, Michael A
Frei, Karl
Spertini, Olivier
Waterfield, Michael D
Arcaro, Alexandre
Universitätsklinik für Kinderheilkunde
Additional Credits
Universitätsklinik für Kinderheilkunde
Series
Anticancer research
Publisher
International Inst. of Anticancer Research
ISSN
0250-7005
Access(Rights)
metadata.only
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