Publication:
Ascending aortic aneurysm and dissection risk: focus on aortic height index.

cris.virtualsource.author-orcid89b43521-afcd-41bf-a6ad-bf8a9626c1f7
datacite.rightsopen.access
dc.contributor.authorGrego, Susanna
dc.contributor.authorPozzoli, Alberto
dc.contributor.authorTorre, Tiziano
dc.contributor.authorLeo, Laura Anna
dc.contributor.authorMuretti, Mirko
dc.contributor.authorToto, Francesca
dc.contributor.authorTheologou, Thomas
dc.contributor.authorFerrari, Enrico
dc.contributor.authorDemertzis, Stefanos
dc.date.accessioned2025-07-17T08:45:03Z
dc.date.available2025-07-17T08:45:03Z
dc.date.issued2025-06-02
dc.description.abstractObjectives Acute aortic dissection (AAD) commonly occurs with a dilation of the ascending aorta at diameters under the threshold of surgical indication. Aortic diameter/height index (AHI) has been proposed for risk stratification and more accurate prophylactic surgery.Methods From January 2001 to November 2023, all patients operated on for AAD at our Institute were prospectively collected and retrospectively analyzed, calculating the AHI. A control group without aortic pathology was stratified for the same risk index, a modelling risk analysis for aortic dissection was also performed.Results A group of 210 patients was operated during the study period, of whom 168 (80%) had a prevalent post-junctional aortic dilation with a mean aortic diameter at the time of diagnosis of 5.1 ± 0.7 cm. In 53/210 (25%) the aortic diameter was > 5.5 cm. According to AHI, 19/210 patients (9%) were low-risk, 142/210 (67.6%) moderate, 45/210 (21.3%) high and 4/210 (2%) severe risk. In the AHI probability density function, the peak for dissection was 2.93 cm/m for males and 3.05 for females. Control were 6343 patients (3.2% at moderate risk) with AHI of 2.01 cm/m. After simulating the dissecting process, 215 (3.3%) had AHI ≥ 2.9 cm/m.Conclusions The measurement of the aortic diameter to height index in patients with acute aortic dissection revealed a significant prevalence of individuals presenting a moderate risk for acute aortic events. Regardless of absolute aortic diameter values, patients with AHI exceeding 2.9 cm/m should be referred to an Aortic Center for multidisciplinary risk assessment.
dc.identifier.doi10.48620/89585
dc.identifier.pmid40455054
dc.identifier.publisherDOI10.1093/icvts/ivaf125
dc.identifier.urihttps://boris-portal.unibe.ch/handle/20.500.12422/211594
dc.language.isoen
dc.publisherOxford University Press
dc.relation.ispartofInterdisciplinary Cardiovascular and Thoracic Surgery
dc.relation.issn2753-670X
dc.relation.issn1569-9293
dc.subjectAscending aorta aneurysm
dc.subjectacute aortic dissection risk
dc.subjectaortic diameter/height index
dc.subjectprevention
dc.subject.ddc600 - Technology::610 - Medicine & health
dc.titleAscending aortic aneurysm and dissection risk: focus on aortic height index.
dc.typearticle
dspace.entity.typePublication
dspace.file.typetext
unibe.contributor.roleauthor
unibe.description.ispublishedinpress
unibe.refereedtrue
unibe.subtype.articlejournal

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