Proactive Management and Treatment of Aortic Stenosis: An International Expert Perspective.

DOI
Publisher DOI
PubMed ID
41636408
Abstract
The 2025 European Society of Cardiology/European Association for Cardio-Thoracic Surgery guidelines mark a pivotal change, challenging the paradigm of symptom-driven watchful waiting, and supporting earlier treatment in many patients with asymptomatic severe aortic stenosis. Building on this foundation, this international expert perspective advocates a comprehensive, proactive management strategy and offers clinicians a contemporary operational framework for managing severe aortic stenosis. Key evidence-based elements include early referral to the multidisciplinary Heart Valve Team, streamlined evaluation, upstream testing, prompt aortic valve replacement in many asymptomatic patients, more urgent treatment for symptomatic patients, and structured surveillance involving close working relationships between the referring clinician and Heart Valve Team when intervention is deferred. This proactive evidence-based model aims to improve timeliness, efficiency, and equity of care, thereby reducing preventable morbidity and mortality and improving long-term outcomes.
Date Issued
2026-02-03
Publication Type
Article
Subject(s)
Subjects
aortic valve replacement
•
aortic valve stenosis
•
echocardiography
•
guidelines
•
randomized clinical trials
•
valvular heart disease
Language(s)
en
Author(s)
Cook, Christopher M
Pibarot, Philippe
Tarantini, Giuseppe
Généreux, Philippe
Delgado, Victoria
Hayashida, Kentaro
Parma, Radoslaw
Kaneko, Tsuyoshi
Rudolph, Tanja K
Cavalcante, João L
Wood, David A
Bax, Jeroen J
Saia, Francesco
Vemulapalli, Sreekanth
Pellikka, Patricia A
Iung, Bernard
Guibone, Kimberly
Dweck, Marc R
Eltchaninoff, Hélène
Ailawadi, Gorav
Lam, Simon Cheung-Chi
Poon, Karl
Unbehaun, Axel
Schwartz, Allan
Joner, Michael
Prendergast, Bernard
Mack, Michael
Hahn, Rebecca T
Leon, Martin B
Lindman, Brian R
Additional Credits
Journal
Journal of the American College of Cardiology
Publisher
Elsevier
ISSN
1558-3597
0735-1097
Access(Rights)
restricted
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