Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells

Publisher DOI
PubMed ID
22086878
Description
Cardiosphere-derived cells (CDCs) are an attractive cell type for tissue regeneration, and autologous CDCs are being tested clinically. However, autologous therapy necessitates patient-specific tissue harvesting and cell processing, with delays to therapy and possible variations in cell potency. The use of allogeneic CDCs, if safe and effective, would obviate such limitations. We compared syngeneic and allogeneic CDC transplantation in rats from immunologically-mismatched inbred strains.
Date of Publication
2012
Publication Type
Article
Language(s)
en
Contributor(s)
Malliaras, Konstantinos
Li, Tao-Sheng
Luthringer, Daniel
Terrovitis, John
Cheng, Ke
Chakravarty, Tarun
Galang, Giselle
Zhang, Yiqiang
Van Eyk, Jennifer
Marbán, Linda
Marbán, Eduardo
Additional Credits
Series
Circulation
Publisher
Lippincott Williams & Wilkins
ISSN
0009-7322
Access(Rights)
metadata.only
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