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  3. Is congenital thrombotic thrombocytopenic purpura a risk factor for ischemic osteonecrosis of the hip joint (Legg-Calvé-Perthes disease)?

Is congenital thrombotic thrombocytopenic purpura a risk factor for ischemic osteonecrosis of the hip joint (Legg-Calvé-Perthes disease)?

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DOI
10.48620/94628
Publisher DOI
10.1186/s12959-026-00838-9
PubMed ID
41680850
Abstract
Weise et al. reported on a 41-year-old patient previously diagnosed with congenital thrombotic thrombocytopenic purpura undergoing total hip replacement surgery for Perthes disease. This case raises the question whether ischemic osteonecrosis of the femoral head is another so far underrecognized comorbidity causally linked to congenital thrombotic thrombocytopenic purpura.
Date Issued
2026-02-12
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Subjects
ADAMTS13 deficiency
•
Congenital thrombotic thrombocytopenic purpura
•
Legg-Calvé-Perthes disease
•
Perthes disease
Language(s)
en
Author(s)
Laemmle, Alexander  
Department of Paediatrics  
Institute of Clinical Chemistry  
Lämmle, Bernhard  
Additional Credits
Department of Paediatrics  
Institute of Clinical Chemistry  
Clinic of Haematology and Central Haematological Laboratory  
Department of Paediatrics, Endocrinology/Metabolic Disorders  
Journal
Thrombosis Journal
Publisher
BioMed Central
ISSN
1477-9560
Access(Rights)
open.access
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