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  3. Attention-deficit hyperactivity disorder (ADHD) and glial integrity: an exploration of associations of cytokines and kynurenine metabolites with symptoms and attention

Attention-deficit hyperactivity disorder (ADHD) and glial integrity: an exploration of associations of cytokines and kynurenine metabolites with symptoms and attention

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DOI
10.7892/boris.1706
Publisher DOI
10.1186/1744-9081-6-32
PubMed ID
20534153
Abstract
In contrast to studies of depression and psychosis, the first part of this study showed no major differences in serum levels of cytokines and tryptophan metabolites between healthy children and those with attention-deficit/hyperactivity disorder of the combined type (ADHD). Yet, small decreases of potentially toxic kynurenine metabolites and increases of cytokines were evident in subgroups. Therefore we examined predictions of biochemical associations with the major symptom clusters, measures of attention and response variability.
Date Issued
2010
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Language(s)
en
Author(s)
Oades, Robert D
Myint, Aye-Mu
Dauvermann, Maria R
Schimmelmann, Benno Karl Edgar  
Universitäre Psychiatrische Dienste, Direktion Kinder- und Jugendpsychiatrie  
Schwarz, Markus J
Additional Credits
Universitäre Psychiatrische Dienste, Direktion Kinder- und Jugendpsychiatrie  
Journal
Behavioral and brain functions
Publisher
BioMed Central
ISSN
1744-9081
Access(Rights)
open.access
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