Volume-rendered optical coherence tomography angiography during ocular interventions: Advocating for noninvasive intraoperative retinal perfusion monitoring.
Publisher DOI
PubMed ID
36089335
Abstract
We aimed to test for feasibility of volume-rendered optical coherence tomography angiography (OCTA) as a novel method for assessing/quantifying retinal vasculature during ocular procedures and to explore the potential for intraoperative use. Thirty patients undergoing periocular anaesthesia were enrolled, since published evidence suggests a reduction in ocular blood flow. Retinal perfusion was monitored based on planar OCTA image-derived data provided by a standard quantification algorithm and postprocessed/volume-rendered OCTA data using a custom software script. Overall, imaging procedures were successful, yet imaging artifacts occurred frequently. In interventional eyes, perfusion parameters decreased during anaesthesia. Planar image-derived and volume rendering-derived parameters were correlated. No correlation was found between perfusion parameters and a motion artifact score developed for this study, yet all perfusion parameters correlated with signal strength as displayed by the device. Concluding, volume-rendered OCTA allows for noninvasive three-dimensional retinal vasculature assessment/quantification in challenging surgical settings and appears generally feasible for intraoperative use.
Date Issued
2022-12
Publication Type
Article
Subject(s)
Subjects
3D vasculature reconstruction intraoperative retinal perfusion monitoring retinal vessel size volume-rendered optical coherence tomography angiography
Language(s)
en
Author(s)
Enz, Tim J | |
Maloca, Peter M | |
Tribble, James R | |
Williams, Pete A | |
Inglin, Nadja | |
Steitz, Ulrike | |
Scholl, Hendrik P N | |
Papazoglou, Anthia |
Additional Credits
Journal
Journal of biophotonics
Publisher
Wiley-VCH
ISSN
1864-063X
Access(Rights)
open.access