Successful Allergen-Specific Immunotherapy: Induction of Unresponsiveness by 'Vaccination'.
Publisher DOI
PubMed ID
38140255
Abstract
The mechanisms of action of allergen-specific immunotherapy (AIT) are often referred to as the induction of 'tolerance'. However, immunological 'tolerance' is defined as an alteration in the function or composition of immune cells. For AIT, this is not always the case, because it can also induce allergen-specific IgG antibodies that block allergic responses. To include all possible mechanisms that may mediate successful AIT, it is advantageous to use the scientific term 'unresponsiveness' instead of 'tolerance'. In praxis, the term 'vaccination' is also appropriate, as AIT medications are specialized vaccines.
Date Issued
2023-12-14
Publication Type
Article
Subject(s)
Language(s)
en
Author(s)
Additional Credits
Journal
Vaccines
Publisher
MDPI
ISSN
2076-393X
Access(Rights)
Unknown