Agreement between Pentacam HR and Visionix VX650 system for corneal and anterior chamber parameters.
Publisher DOI
PubMed ID
42321687
Abstract
Purpose
To evaluate the agreement in anterior segment measurements obtained with Pentacam HR and Visionix VX650 topographers, in terms of keratometry, pachymetry and anterior chamber parameters in healthy eyes.Methods
Inclusion criteria consisted of healthy eyes with no history of ocular pathology or surgery. Measurements of central corneal thickness (CCT), minimum corneal thickness (MCT), anterior and posterior keratometry (K1, K2), anterior chamber depth (ACD), and anterior chamber angle (ACA) were taken using the Pentacam HR and Visionix VX650. Differences between devices were assessed with paired Student's t-tests, and agreement was evaluated using Bland-Altman plots.Results
Fifty-five eyes from 55 healthy participants mean age 32.55 ± 12.60 years) were examined. Anterior keratometry and MCT showed clinically acceptable agreement between devices, with no significant differences (p > 0.164). Pentacam HR reported steeper posterior keratometry, smaller ACD, lower CCT and larger ACA values compared with VX650 (p < 0.001). For CCT and MCT, ranges of agreement were large, with values of ± 27.07 and 55.41 μm, respectively. However, the ranges of agreement for anterior K1 and K2 were smaller, with values of ± 0.11 and 0.11 mm, respectively. Likewise, the ranges of agreement for ACD and ACA were also clinically significant, with a clear trend of VX650 to provide longer ACD measurements and lower ACA estimates.Conclusions
Anterior corneal keratometry measured with the Pentacam HR and Visionix VX650 exhibit acceptable inter-device agreement. However, caution should be exercised regarding their interchangeability, especially when making decisions that require precise thickness (refractive surgery screening) or anterior chamber parameters (phakic intraocular lens implantation).
To evaluate the agreement in anterior segment measurements obtained with Pentacam HR and Visionix VX650 topographers, in terms of keratometry, pachymetry and anterior chamber parameters in healthy eyes.Methods
Inclusion criteria consisted of healthy eyes with no history of ocular pathology or surgery. Measurements of central corneal thickness (CCT), minimum corneal thickness (MCT), anterior and posterior keratometry (K1, K2), anterior chamber depth (ACD), and anterior chamber angle (ACA) were taken using the Pentacam HR and Visionix VX650. Differences between devices were assessed with paired Student's t-tests, and agreement was evaluated using Bland-Altman plots.Results
Fifty-five eyes from 55 healthy participants mean age 32.55 ± 12.60 years) were examined. Anterior keratometry and MCT showed clinically acceptable agreement between devices, with no significant differences (p > 0.164). Pentacam HR reported steeper posterior keratometry, smaller ACD, lower CCT and larger ACA values compared with VX650 (p < 0.001). For CCT and MCT, ranges of agreement were large, with values of ± 27.07 and 55.41 μm, respectively. However, the ranges of agreement for anterior K1 and K2 were smaller, with values of ± 0.11 and 0.11 mm, respectively. Likewise, the ranges of agreement for ACD and ACA were also clinically significant, with a clear trend of VX650 to provide longer ACD measurements and lower ACA estimates.Conclusions
Anterior corneal keratometry measured with the Pentacam HR and Visionix VX650 exhibit acceptable inter-device agreement. However, caution should be exercised regarding their interchangeability, especially when making decisions that require precise thickness (refractive surgery screening) or anterior chamber parameters (phakic intraocular lens implantation).
Date Issued
2026-06-19
Publication Type
Article
Subject(s)
Subjects
Anterior segment imaging
•
Corneal topography
•
Keratometry
•
Pachymetry
•
Pentacam HR
•
Visionix VX650
Language(s)
en
Author(s)
Barberán-Bernardos, Laura | |
Piñero, David P |
Additional Credits
Journal
BMC Ophthalmology
Publisher
BioMed Central
ISSN
1471-2415
Access(Rights)
open.access