A Novel Genetic Group of Bovine Hepacivirus in Archival Serum Samples from Brazilian Cattle
Publisher DOI
PubMed ID
28904959
Abstract
Hepatitis C virus (HCV) (genus; family Flaviviridae) is a major human pathogen causing persistent infection and hepatic injury. Recently, emerging HCV-like viruses were described infecting wild animals, such as bats and rodents, and domestic animals, including dogs, horses, and cattle. Using degenerate primers for detecting bovine pestiviruses in a 1996 survey three bovine serum samples showed a low identity with the genusof the Flaviviridae family. A virus could not be isolated in cell culture. The description of bovine hepaciviruses (BovHepV) in 2015 allowed us to retrospectively identify the sequences as BovHepV, with a 88.9% nucleotide identity. In a reconstructed phylogenetic tree, the Brazilian BovHepV samples grouped within the bovine HCV-like cluster in a separated terminal node that was more closely related to the putative bovinecommon ancestor than to bovine hepaciviruses detected in Europe and Africa.
Date Issued
2017
Publication Type
Article
Language(s)
en
Author(s)
Canal, Cláudio W | |
Weber, Matheus N | |
Cibulski, Samuel P | |
Silva, Mariana S | |
Puhl, Daniela E |
Additional Credits
Journal
BioMed research international
Publisher
Hindawi Publishing Corporation
ISSN
2314-6133
Access(Rights)
open.access