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Tuberculosis after initiation of antiretroviral therapy in low-income and high-income countries

DOI
Publisher DOI
PubMed ID
17990236
Abstract
We examined the incidence of and risk factors for tuberculosis during the first year of highly active antiretroviral therapy in low-income (4540 patients) and high-income (22,217 patients) countries. Although incidence was much higher in low-income countries, the reduction in the incidence of tuberculosis associated with highly active antiretroviral therapy was similar: the rate ratio for months 7-12 versus months 1-3 was 0.48 (95% confidence interval, 0.36-0.64) in low-income countries and 0.36 (95% confidence interval, 0.26-0.50) in high-income countries. A low CD4 cell count at the start of therapy was the most important risk factor in both settings.
Date Issued
2007
Publication Type
Article
Language(s)
en
Author(s)
Brinkhof, MW
Egger, M
Boulle, A
May, M
Hosseinipour, M
Sprinz, E
Braitstein, P
Dabis, F
Reiss, P
Bangsberg, DR
Rickenbach, M
Miro, JM
Myer, L
Mocroft, A
Nash, D
Keiser, O
Pascoe, M
van der Borght, S
Schechter, M
Additional Credits
Journal
Clinical infectious diseases
Publisher
Oxford University Press
ISSN
1058-4838
ISBN
17990236
Access(Rights)
open.access
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