Investigation of Glucose-phosphates in Skeletal Muscle Biopsies by 1H HR-MAS NMR: Comparison between Active and Sedentary Subjects
Abstract
The aim of this 1H HR-MAS NMR study was to investigate biopsies of skeletal muscles comparing athletes, sedentary slim and sedentary obese subjects. 1H HR-MAS allows the direct assessment of glucose-phosphates contained in skeletal muscle biopsies, as was also previously shown. The current study is the first example for a potential application, demonstrating differences in glucose-phosphates between muscle tissues from athletes and sedentary subjects. The results suggest that quantitative assessment by 1H HR-MAS NMR of Glc-1P and Glc-6P being key players in energy metabolism may prove important for metabolic studies in biopsies.
Date Issued
2016-05-07
Publication Type
Conference Item
Subject(s)
Language(s)
en
Author(s)
Broskey, NT | |
Amati, F |
Access(Rights)
metadata.only