Dose optimization approach to fast X-ray microtomography of the lung alveoli
Publisher DOI
PubMed ID
24046488
Abstract
A basic prerequisite for in vivo X-ray imaging of the lung is the exact determination of radiation dose. Achieving resolutions of the order of micrometres may become particularly challenging owing to increased dose, which in the worst case can be lethal for the imaged animal model. A framework for linking image quality to radiation dose in order to optimize experimental parameters with respect to dose reduction is presented. The approach may find application for current and future in vivo studies to facilitate proper experiment planning and radiation risk assessment on the one hand and exploit imaging capabilities on the other.
Date Issued
2013-08-01
Publication Type
Article
Subject(s)
Subjects
X-ray microtomography
•
dose optimization
•
lung aveoli
•
radiation dose
Language(s)
en
Author(s)
Lovric, Goran | |
Roth-Kleiner, Matthias | |
Stampanoni, Marco | |
Mokso, Rajmund |
Additional Credits
Journal
Journal of applied crystallography
Publisher
Blackwell
ISSN
0021-8898
Access(Rights)
metadata.only