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  3. Biologically based strategies to augment rotator cuff tears

Biologically based strategies to augment rotator cuff tears

Details
Publisher DOI
10.4103/0973-6042.96995
PubMed ID
22787334
Abstract
Lesions of the rotator cuff (RC) are among the most frequent tendon injuries. In spite of the developments in both open and arthroscopic surgery, RC repair still very often fails. In order to reduce the failure rate after surgery, several experimental in vitro and in vivo therapy methods have been developed for biological improvement of the reinsertion. This article provides an overview of the current evidence for augmentation of RC reconstruction with growth factors. Furthermore, potential future therapeutic approaches are discussed. We performed a comprehensive search of the PubMed database using various combinations of the keywords "tendon," "rotator cuff," "augmentation," "growth factor," "platelet-rich fibrin," and "platelet-rich plasma" for publications up to 2011. Given the linguistic capabilities of the research team, we considered publications in English, German, French, and Spanish. We excluded literature reviews, case reports, and letters to the editor.
Date Issued
2012
Publication Type
Article
Language(s)
en
Author(s)
Schaer, M
Schober, Martin  
Universitätsklinik für Orthopädische Chirurgie  
Berger, S
Boileau, P
Zumstein, Matthias  
Universitätsklinik für Orthopädische Chirurgie  
Additional Credits
Universitätsklinik für Orthopädische Chirurgie  
Journal
International journal of shoulder surgery
Publisher
Medknow Publications
ISSN
0973-6042
Access(Rights)
metadata.only
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