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  3. Non-specific presentation of metastatic small bowel adenocarcinoma with diagnostic challenges.

Non-specific presentation of metastatic small bowel adenocarcinoma with diagnostic challenges.

Details
Publisher DOI
10.1136/bcr-2024-261407
PubMed ID
39214581
Abstract
Diagnosing small bowel adenocarcinomas presents challenges due to non-specific symptoms, rarity and gastroscopy and colonoscopy's limited small intestine access, highlighting targeted diagnostic procedures' necessity. We present a late-diagnosed metastatic small bowel adenocarcinoma case in a man in his 80s who had asymptomatic mild iron-deficiency anaemia 1 year before diagnosis, with no active bleeding found on endoscopies. He experienced a single rectal bleeding episode 9 months prediagnosis, with subsequent severe iron-deficiency anaemia and no clear gastrointestinal source identified on gastroscopy. For 2 months, he had intermittent postprandial diarrhoea without abdominal pain, infectious or inflammatory causes. He experienced significant weight loss over 3 months prediagnosis. Subsequent gastroscopy indicated duodenal-gastric food retropulsion, suggesting a downstream blockage. Magnetic resonance enterography showed proximal jejunum thickening. Push enteroscopy confirmed jejunum adenocarcinoma. CT scans detected liver and peritoneal metastases. After one chemotherapy cycle, his condition worsened, leading to his passing 2 months post diagnosis.
Date Issued
2024-08-30
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
Subjects
Endoscopy
•
GI bleeding
•
General practice / family medicine
•
Small intestine
•
Small intestine cancer
Language(s)
en
Author(s)
Chakroun, Dora
Marnas, Nathalie
Kapoglou, Ioannis  
Clinic of Visceral Surgery and Medicine, Gastroenterology  
Berger, Martin D.  
Clinic of Medical Oncology  
Wartenberg, Martin  orcid-logo
Institute of Tissue Medicine and Pathology, Clinical Pathology  
Schiemann, Uwe  
Additional Credits
Clinic of Medical Oncology  
Clinic of Visceral Surgery and Medicine, Gastroenterology  
Institute of Tissue Medicine and Pathology, Clinical Pathology  
Journal
BMJ case reports
Publisher
BMJ Publishing Group (United Kingdom)
ISSN
1757-790X
Access(Rights)
Unknown
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