Pattern of failure after adjuvant radiotherapy following extrapleural pneumonectomy of pleural mesothelioma in the SAKK 17/04 trial.

DOI
Publisher DOI
PubMed ID
31252293
Abstract
Postoperative radiotherapy after extrapleural pneumonectomy of malignant pleural mesothelioma was investigated in the randomized phase II trial SAKK17/04. The relapse rate within the high and/or low-dose PTV without previous distant failure was 24%, the isolated in-field-relapse rate within the PTVs was 5% and the distant relapse rate outside of the PTVs was 81%. Clinical outcome was mainly determined by distant disease progression outside of the radiation field.
Date Issued
2019-09
Publication Type
Article
Subject(s)
Subjects
Extrapleural pneumonectomy Mesothelioma Multimodal therapy Radiation therapy Radiotherapy Trimodal therapy
Language(s)
en
Author(s)
Riesterer, Oliver
Frank Ciernik, I
Stahel, Rolf A
Xyrafas, Alexandros
Mahmut Ozsahin, E
Zwahlen, Daniel R
Nackaerts, Kristiaan
Zimmermann, Frank
Sabrina Stark, L
Weder, Walter
Krayenbuehl, Jérôme
Additional Credits
Journal
Radiotherapy and oncology
Publisher
Elsevier
ISSN
0167-8140
Access(Rights)
restricted
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