Fusarium onychomycoses in Switzerland-A mycological and histopathological study.
Publisher DOI
PubMed ID
31271679
Abstract
Onychomycoses in temperate climates are most commonly due to dermatophytes, particularly Trichophyton rubrum. Non-dermatophyte nail infections are much less frequent, and their diagnosis requires a careful and repeated search for a potential dermatophyte that may have been overgrown in culture. A series of histological slides of suspected onychomycoses with uncommon fungal morphology prompted us to search for non-dermatophytic moulds causing dermatophytosis-like nail infections. Thirty cases were identified by culture as F solani, F oxysporum, F dimerum or F spp, and two more were only diagnosed histopathologically. None of these patients was immunocompromised. Treatment was mostly unsuccessful with terbinafine whereas itraconazole showed a moderately better treatment result; in all cases, a topical ciclopirox nail varnish in a hydroxychitosan base was added.
Date Issued
2019-10
Publication Type
Article
Subjects
Fusarium species culture histopathology onychomycosis treatment
Language(s)
en
Additional Credits
Journal
Mycoses
Publisher
Wiley-Blackwell
ISSN
0933-7407
Access(Rights)
open.access