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  3. Lactate dehydrogenase concentration in nasal wash fluid indicates severity of rhinovirus-induced wheezy bronchitis in preschool children.

Lactate dehydrogenase concentration in nasal wash fluid indicates severity of rhinovirus-induced wheezy bronchitis in preschool children.

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DOI
10.7892/boris.69252
Publisher DOI
10.1097/INF.0000000000000420
PubMed ID
25389710
Abstract
The clinical course of rhinovirus (RV)-associated wheezing illnesses is difficult to predict. We measured lactate dehydrogenase concentrations, RV load, antiviral and proinflammatory cytokines in nasal washes obtained from 126 preschool children with RV wheezy bronchitis. lactate dehydrogenase values were inversely associated with subsequent need for oxygen therapy. lactate dehydrogenase may be a useful biomarker predicting disease severity in RV wheezy bronchitis.
Date Issued
2014-12
Publication Type
Article
Subject(s)
600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology
Language(s)
en
Author(s)
Cangiano, Giulia
Proietti, Elena
Kronig, Marie Noelle
Kieninger, Elisabeth  orcid-logo
Universitätsklinik für Kinderheilkunde  
Sadeghi, Christine D
Gorgievski, Meri  
Institut für Infektionskrankheiten  
Barbani, Maria Teresa  
Institut für Infektionskrankheiten  
Midulla, Fabio
Tapparel, Caroline
Kaiser, Laurent
Alves, Marco P
Regamey, Nicolas  
Universitätsklinik für Kinderheilkunde  
Additional Credits
Universitätsklinik für Kinderheilkunde  
Institut für Infektionskrankheiten  
Journal
The Pediatric infectious disease journal
Publisher
Lippincott Williams & Wilkins
ISSN
1532-0987
Access(Rights)
restricted
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